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Cold Spring Harbor Translational Control 2026
会议时间 | September 1–5, 2026 |
会议地点 | Cold Spring Harbor Laboratory, New York |
会议规模 | 8 oral sessions · 3 poster sessions · 292 abstract presenters |
2026年9月1日至5日，第20届冷泉港实验室Translational Control会议将在美国纽约冷泉港实验室举行。作为蛋白质翻译与翻译调控领域的重要国际会议，本届大会将汇集来自全球的研究者，围绕翻译起始、核糖体生成、翻译延伸与终止、质量控制、mRNA稳态以及疾病相关翻译异常等前沿方向展开交流。
会议首场学术环节将于9月1日（周二）晚7:30开始，最终环节预计于9月5日（周六）中午结束。根据官网公布的安排，大会设置8个口头报告专题和3场海报交流；口头报告由组织者与各专题主席根据投稿摘要共同遴选。
一场覆盖翻译调控全链条的学术会议
蛋白质翻译并非简单地将mRNA信息转化为蛋白质，而是贯穿细胞生长、应激响应、发育与疾病发生的重要调控层。
本届会议设置的八大主题，基本覆盖了从核糖体形成、翻译过程控制到mRNA命运和疾病机制的完整研究链条：
· Initiation and Biogenesis｜翻译起始与核糖体生成
· Elongation and Termination｜翻译延伸与终止
· Quality Control Pathways｜翻译质量控制通路
· Translation Regulation｜翻译调控
· Ribosome Heterogeneity｜核糖体异质性
· mRNA Turnover｜mRNA周转与降解
· Development / CNS｜发育与中枢神经系统
· Disease, Infection and Cancer｜疾病、感染与肿瘤
这些议题既关注翻译机器本身的结构与功能，也强调RNA修饰、密码子解码、核糖体停滞与碰撞、翻译质量控制和mRNA降解之间的协同关系，进一步延伸至神经系统、感染和肿瘤等重要生物医学问题。
三位主题演讲嘉宾
· Maria Barna｜Stanford University
· Alexander Mankin｜University of Illinois Chicago
· Joshua Mendell｜UT Southwestern Medical Center
三位学者的研究分别连接核糖体与发育调控、抗生素作用与核糖体机制、非编码RNA与疾病生物学，为本届会议呈现出从翻译机器基础机制到疾病应用研究的鲜明跨度。
完整参会嘉宾名单详见文末附录。
会议组织者与专题主席
Organizers
· Rachel Green｜Johns Hopkins University School of Medicine
· Davide Ruggero｜University of California, San Francisco
· Daniel Wilson｜University of Hamburg, Germany
Session Chairs
· Simon Bekker-Jensen｜University of Copenhagen, Denmark
· Zachary Campbell｜University of Wisconsin
· Christopher Fraser｜UC Davis
· Andrew Hsieh｜Fred Hutchinson Cancer Center
· Ahmad Jomaa｜University of Virginia
· Kamena Kostova｜Stowers Institute for Medical Research
· Kate Meyer｜Duke University
· Ayala Shiber｜Technion, Israel
本届会议中翻译调控研究的新趋势
会议公布292项摘要展示名单，本届大会共安排75个talk和217个poster。报告题目覆盖m⁶A等RNA修饰与翻译、核糖体停滞和碰撞、核糖体质量控制、非经典翻译、病毒移码、局部翻译、神经系统调控以及肿瘤相关翻译重编程等方向。
1. 研究尺度更加精细：从基因或转录本表达，深入到翻译起始位点、密码子分辨率核糖体行为及单个翻译事件。
2. 翻译过程更加动态：核糖体停滞、碰撞、救援和终止不再被视为被动异常，而是重要的调控节点。
3. 核糖体本身成为变量：核糖体组成、异质性和组织特异性逐渐成为解释选择性翻译的重要切入点。
4. 技术路线更加融合：Ribo-seq、结构生物学、定量蛋白质组学、单细胞正在形成更完整的证据链。
5. 疾病关联持续深化：翻译异常与肿瘤、感染、神经系统疾病及发育异常之间的联系受到广泛关注。
结语
翻译调控会议持续推动翻译领域基础机制与技术创新的交汇。2026年的冷泉港会议将再次集中展示核糖体生物学、RNA调控和疾病机制研究的最新进展。
随着翻译组学技术不断向更高分辨率、更低起始量和多组学整合方向发展，研究者将能够更加系统地回答：哪些RNA正在被翻译、翻译在何处发生改变，以及这些变化如何最终影响细胞命运与疾病进程。
新使生物NeoRibo长期专注于翻译组学技术研发与应用，围绕超高分辨率Ribo-seq、Polysome profiling、全景tRNA-seq、RNA修饰检测、Poly(A)尾测序及免疫肽质谱等技术，构建从整体翻译活性、核糖体动态到翻译产物鉴定的系统研究方案。
我们也将持续关注本届会议带来的新技术与新方向，与国内研究者共同推动翻译调控研究。
| 新使生物专业翻译组一站式服务平台 |
| 产品名称 |
GLORI-seq 2.0/3.0 （m⁶A单碱基绝对定量检测） |
附录｜Official Abstract Presenter List
注：冷泉港实验室提醒，未经报告人许可，不应在社交媒体上实时发布或讨论其报告、海报及未公开研究结果。
Talk Presenters (75)
Abdallah, Kyrillos | Lee, Jae Ho |
Agrawal, Rajendra | Levine, Zebulon G |
Ashwood, Brennan G | Li, Wenfei |
Beckmann, Roland | Luck, Meagan |
Bekker-Jensen, Simon | Makhzumy, Muhammad |
Biffo, Stefano | Maldosevic, Emir |
Bonitto, Kenya | McGrath, Morgan |
Brito Querido, Jay | Meydan, Sezen |
Brooke, Grant | Meyer, Kate |
Bushell, Martin | Morici, Martino |
Buszczak, Michael | Ortega, Joaquin |
Campbell, Zachary | Qian, Shu-Bing |
Catipovic, Marco | Rale, Michael |
Chang, Suhee | Regot, Sergi |
Cheng, Jing | Robecchi, Giovanni |
Chitale, Ruta | Selmer, Maria |
Cooley, Lynn | Shah, Akruti |
Corey, Seth | Singh, Kamini |
De Miguel, Claudia | Snyder, Samantha |
Dikstein, Rivka | Sokabe, Masaaki |
Engel, Carla | Sorensen, Poul |
Fenton, Darren A | Sossin, Wayne |
Fernandez-Garcia, Leandro | Stackhouse, Crystal I |
Fischer, Niels | Titmuss, Ben O |
Fujii, Kotaro | Tsai, Hsin-Yu |
Grimins, Autumn O | Walker, Sarah |
Haahr, Peter | Wang, Jinfan |
Hashimoto, Satoshi | Weber, Ramona |
Hernandez Alias, Xavier | Welfer, Griffin A |
Hu, Wenqian | Winters, Ashlyn G |
Huang, Chun-Ying | Wu, Qiushuang |
Jain, Ankur | Wu, Xuebing |
Jansson, Martin | Xavier, Audrey |
Jentoft, Ida Marie Astad M | Yan, Liewei (Leo) |
Johansson, Magnus | Yerby, Clifford |
Kim, Yeon Soo | Zaher, Hani |
Kraus, W. Lee | Zhong, Franklin L |
Lantz, Travis C |
Poster Presenters (217)
Adade, Naa Nuerki | Loveland, Anna |
Ahmed, Sinthyia | Lv, Xiangdong |
Allegretti, Madison M | Lyons, Shawn M |
Arava, Yoav | Ma, Jinbiao |
Balasaniants, Samson | Maeta, Kaho |
Balasubramanian, Hari Krishnan | Mahoney, Emily M |
Banavali, Nilesh | Majumdar, Soneya |
Banerjee, Abhineet | Martin, Marie-France |
Banerjee, Aneek | Matlin, Katherine L |
Banerjee, Sourima | Matsumoto, Ayu |
Barros, Gessica | Mattijssen, Sandy |
Benedetto, Alexandra | May, Mira B |
Benner, Brittany | McKown, Grace |
Boydston, Darren P | McManus, Joel |
Brekker, Mollie Adaline | Menichincheri, Gaia |
Chandrasekaran, Vish | Miller, Sarah C |
Chen, Yiwen T | Mishra, Rashmi |
Chen, Yuxiang | Misra, Jagannath |
Clarke, Paul A | Mohapatra, Ira |
Cole, Izaiah J | Mordente, Kelly |
Cooperman, Barry | Mukherjee, Neelanjan |
Cortina, Maria E | Neves, Esther |
Cozy, Jake M | Nishikawa, Yuma |
Cruz Navarrete, Francisco Aaron | Oberkersch, Roxana E |
da Silva Pescador, Gabriel | Ohtani, Mahiro |
Dabrowska, Adrianna | Olarerin-George, Anthony |
Dali, Animesh | Oliver, Kathryn |
Darnell, Alicia | Omollo, Expery |
Dasovich, Morgan | Origanti, Sofia |
De, Swastik | Orobets, Kseniia |
Devarkar, Swapnil C | Ossevoort, Thomas W |
Dhepe, Ajinkya Anil | Paralkar, Vikram |
Dixit, Manisha | Patel, Diya K |
Djuranovic, Sergej | Petrossian, Edward |
Feid, Caldwell | Phanor, Sabrina K |
Fredrick, Kurt | Pilankar, Leena |
Freitas, Anna | Pirzada, Mujeeb Ur Rehman |
Fuchs, Gabriele | Poonia, Poonam |
Galligos, Anna M | Potgieter, Sarah |
Garraffo, Raffaele | Rahil, Huma |
Geng, Qi | Ramalho, Sofia |
Genuth, Naomi | Rasmussen, Megan |
Ghosh, Tanushree | Raven, Rebecca |
Gibert, Virgile | Rothschild, Daphna |
Gluc, Maciej | Rothzerg, Emel |
Gopinath, Srikar | Roy, Bappaditya |
Griffa, Alberto | Saforo, Douglas |
Grove, Amy K | Saladin, Brenna |
Guevara, Matthew G | Sam, Richard |
Hamey, Joshua J | Santiago Millan, Leeza M |
Hammel, Forrest A | Scavone, Francesco |
He, Feng | Schiemann, Anja |
He, Rongrong | Sears, Rhiannon M |
Heller, Jalyce | Segar, Katherine E |
Hermosillo, Cynthia | Seidel, Antonia |
Hoang, Andy | Sekar Manjula,Sharan Surya |
Holmes, Michael J | Selmer, Maria |
Horn, Jacob S | Seraj, Zahra |
Howard, Marissa | Serbagi, Morgan |
Hsueh, Yi-Ping | Shankar, Kasturika |
Hu, Minling | Shin, Byung |
Huang, Alexandra N | Sholi, Emily |
Huang, Zuoshi J | Singh, Prabhakar |
Hudson, Andrew M | Slota, Macey J |
Huynh, Phu | Smith, Jerome |
Ikeuchi, Ken | Soles, Lindsey V |
Inada, Toshifumi | Srinivasan, Krishnamoorthi |
Isada, Matthew F | Srivastava, Sarthak |
Ivanov, Ivaylo | Stalls, Victoria D |
James, Jasmine | Stolp, Isabelle |
Jan, Eric | Susorov, Denis |
Jayasinghe, Oshadhi T | Svetlov, Maxim |
Jin, Hong | Syroegin, Egor |
Johnston, Ryan | Szaflarski, Witold |
Karamyshev, Andrey L | Tamayo Jaramillo, Daniela |
Karamysheva, Zemfira | Tetreault, Daniel D |
Kato, Miko | Thakor, Nehal |
Katsuda, Yousuke | Thaxton, Michelle |
Kaur, Jaswinder | Thoreen, Carson |
Kearse, Michael G | Timba, Mandisa |
Kennedy, Kristopher | To, Hirotaka |
Kerkhofs, Kyra | Tollerson, Rodney |
Khan, Qura-Tul-Ain A | Torres Mendez, Antonio |
Khurram, Maaz Asher | Uchida, Keita |
Khurram, Maaz Asher | Urban, Annie |
Kiledjian, Nora T | Valdez, Nicolette A |
Kim, Hyeongju | van der Ent, Mees |
Kimura, Satoshi | Vanegas Cano,Leidy Johana |
Kleemann, Leon | Varshavsky, Dan B |
Knowles, Corey M | von Loeffelholz, Ottilie |
Kobo, Akinao | Wallbank, Grace |
Koga, Yumi | Walsh, Peter |
Kovalski, Joanna R | Wang, Caroline B |
Kruglov, Artem | Wang, Yuhong |
Kuemmecke, Maximilian | Wang, Zhe Chong |
Kulkarni, Rutuja | Weiss, Benjamin |
Kumar, Rakesh | West, Sean |
Kuna, Karolina | Wilson, Daniel N |
Kvietkauskas, Justas | Wiratmo, Vanessa E |
Lapointe, Christopher P | Wirth, Brian |
Lawson, Michael R | Wu, Xincheng |
Leber, Cecilia | Xue, Ziyu |
Lehr, Abigail | Young-Baird, Sara K |
Leskaj, Suada | Zhang, Yuekang |
Li, Mulin | Zhao, Na |
Li, Sihan | Zhao, Ning |
Li, Xin | Zhou, Fujun |
Lin, Ran | Zhu, Chenghao |
Lin, Ran |